Dr. Nono's Comprehensive Guide to Skin Rejuvenation and Conditioning: Easy Ways to Reduce Wrinkles, Slow Down Aging, and Achieve Smooth Skin for Everyone
- SPARK IDEA Digital Marketing
- Jun 5
- 25 min read
Hello everyone! It's Dr. Nono, Dr. Chanapat Chinvejkijwanich, Medical License No. 60686, again. From Entrio Clinic, an aesthetic medical clinic in the heart of Ratchaprasong, an area full of vitality and people who always strive to look their best. Here, we believe in offering modern, safe, and truly distinctive aesthetic technology.
As a doctor who has been involved in the aesthetic and anti-aging medicine industry for quite some time, I have seen the strong desire of people to maintain their youthfulness and correct the signs of aging that appear on their faces and skin. Whether it's the beginning of wrinkles, dull and lifeless skin, sagging that makes the face look tired, or even uneven skin texture and large pores, these problems gradually erode our confidence.
Today, I want to "bundle together" my knowledge and experience to present a comprehensive approach to rejuvenating and conditioning the skin, helping to reduce wrinkles, slow down aging, and achieve smooth skin, which is the primary goal for most patients. I will explain in detail how we at Entrio Clinic, Ratchaprasong Aesthetic Clinic, think about and approach your skin care to achieve sustainable and natural results.
Understanding "Signs of Aging" on the Skin: The Root Cause of Problems We Must Address
I want to take you all on a "deep dive" into the root causes of these problems in more detail. Because to be able to reduce wrinkles, slow down aging, and condition our skin to look good sustainably, we must first truly understand the mechanisms of skin changes with age. It's like being a specialist doctor who must correctly diagnose a disease before being able to plan the most accurate and effective treatment.
Our skin doesn't change with age for just one reason. Instead, it's a combination of many factors, both from within our own bodies and from external factors that surround us constantly. Let's see where these "signs of aging" come from and how each affects our skin.
1. Decrease in Collagen and Elastin: The Deteriorating Main Structure
This is the heart of skin changes with age and the main factor causing visible wrinkles and sagging.
Collagen: The "Main Pillar" of Strength
Role
Collagen is the most abundant structural protein found in the skin, accounting for approximately 75-80% of the skin's dry weight. It acts like "main pillars," "support beams," and a "mesh network" that supports the skin's structure, providing strength, elasticity, and shape. Skin rich in collagen appears firm, taut, and smooth.
Changes with Age
Normally, after the age of 20, our bodies start producing about 1% less collagen per year, and the rate of collagen degradation also increases. Furthermore, newly produced collagen is of lower quality, with a less robust structure than before.
Impact on Skin
When collagen decreases and deteriorates, the skin begins to lose its strength and firmness, leading to skin laxity, less tautness than before, and is the main cause of wrinkles, both fine lines and visible deep wrinkles.
Elastin: The "Elastic Band" of Flexibility
Role
Elastin is another important protein, no less crucial than collagen. It acts like an "elastic band" that provides elasticity and the skin's ability to bounce back. When we pull our skin or make facial expressions, elastin helps the skin quickly return to its original state.
Changes with Age
Elastin production also decreases with age, and existing elastin fibers may deteriorate and intertwine, making them unable to stretch as effectively as before.
Impact on Skin
When elastin decreases and deteriorates, the skin loses its elasticity, becoming less springy and unable to bounce back. The skin will appear wrinkled, less firm, and more prone to wrinkles caused by skin folding.
2. Fat and Bone Resorption (Volume Loss & Structural Changes): A Tired Face and Altered Structure
In addition to collagen and elastin, other structures beneath the skin also change, significantly impacting overall facial shape and making us look older.
Decrease and Displacement of Subcutaneous Fat Pads
Role
Subcutaneous fat is like a "cushion" and "sponge" that supports the skin, making it look full and plump, and plays an important role in defining overall facial shape.
Changes with Age
As we age, the amount of subcutaneous fat decreases in some areas (e.g., mid-cheeks, temples, under eyes) and may shift downwards due to gravity (e.g., lower cheek area, leading to nasolabial folds and marionette lines).
Impact on Skin
This causes the face to appear hollow, tired, with various deep grooves such as nasolabial folds, marionette lines, an asymmetrical face, and makes skin laxity more pronounced.
Changes and Resorption of Facial Bones (Bone Resorption)
Role
Facial bones are the main structure that supports and defines our facial shape.
Changes with Age
As we age, some facial bones undergo resorption and become thinner, such as the bones around the eyes, temples, cheekbones, and jawbone.
Impact on Skin
Bone resorption directly leads to facial hollowing, causing deep-set eyes that look sunken, hollow temples, flattened cheekbones, an undefined jawline, and increased sagging and drooping of the overlying skin that was once attached to the bone.
3. Sun Exposure and Pollution (Photoaging & Environmental Damage): Catalysts of Aging
These external factors severely accelerate skin aging and cause various skin problems.
UV Radiation from Sunlight
Role
UV radiation, especially UVA and UVB, is a major culprit that damages skin cells, DNA, and collagen/elastin structures.
Mechanism of Damage
UV radiation creates free radicals, which are substances that continuously damage skin cells and collagen/elastin structures. This reduces new collagen production and significantly accelerates the degradation of existing collagen/elastin. Additionally, it stimulates abnormal melanin production.
Impact on Skin
This leads to dark spots, melasma, freckles, uneven skin tone, rough skin, premature wrinkles (photoaging), especially what is called Elastosis (skin that looks thick, yellowish, and wrinkled), and makes the skin appear dull and lifeless.
Pollution, especially PM 2.5
Role
Small particles in pollution can easily penetrate the skin.
Mechanism of Damage
Pollution stimulates oxidative stress and inflammation in the skin, causing the skin to produce free radicals, damage collagen and elastin, and disrupt the function of the skin barrier.
Impact on Skin
This makes the skin more sensitive, causes inflammation, premature wrinkles, and makes the skin appear dull and lacking vibrancy.
4. Repetitive Facial Expressions (Dynamic Wrinkles): The Marks of Smiles and Frowns
This type of wrinkle differs from wrinkles caused by sagging but is a clear sign of aging.
Mechanism
Caused by repeated contraction of facial muscles when we make various expressions, such as smiling, laughing, frowning, or raising eyebrows.
Changes with Age
In youth, the skin is highly elastic. When muscles relax, wrinkles disappear. However, as we age, collagen and elastin decrease, and the skin loses its ability to bounce back, so these wrinkles begin to appear even when we are not making facial expressions (Static Wrinkles).
Impact on Skin
Causes forehead wrinkles, frown lines (the "11" lines), and crow's feet, which make the face look older or more tired than its age.
5. Lack of Moisture (Dehydration & Impaired Skin Barrier): Dry Skin, a Sign of Age
Moisture is the foundation of healthy skin. Lack of moisture affects every dimension of the skin.
Skin Barrier
The Stratum Corneum (outermost layer of the epidermis) and intercellular lipids act as a "protective barrier" to prevent water evaporation from the skin and protect against external foreign substances.
Mechanism of Dehydration
As we age, the production of natural moisturizing factors (NMFs) in the skin decreases, and the function of the skin barrier deteriorates. This leads to easier transepidermal water loss (TEWL). Additionally, external factors such as dry weather, insufficient water intake, caffeine, alcohol, and the use of inappropriate skincare products all contribute to skin dehydration.
Impact on Skin
Makes the skin appear dry and rough, dull, lacking vibrancy, feeling tight and uncomfortable, with fine lines caused by dryness becoming more prominent, and the skin tending to be more sensitive and easily irritated.
Other Contributing Factors to "Signs of Aging"
Genetics
Some people are genetically predisposed to age faster than others.
Lifestyle
Smoking (severely damages collagen), unhealthy diet (high sugar, processed foods), chronic stress, and sleep deprivation all accelerate the skin aging process.
Hormonal Changes
Especially during menopause, reduced estrogen directly affects collagen and HA production in the skin, leading to drier and thinner skin.
Once we understand the root causes of these "signs of aging" in detail, we can plan appropriate and effective skin care. At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we don't just look at the "wrinkles" or "sagging" you see. Instead, we look at the true mechanisms occurring in your skin layers and choose technologies and procedures designed to directly address those problems.
Dr. Nono's "Solutions" for Your Beautiful Skin at Entrio Clinic Ratchaprasong
Entrio Clinic, Ratchaprasong Aesthetic Clinic, we don't just have "tools" or "products." Instead, we have a "philosophy" that is at the heart of your skin care!
I always believe that the best skin care is not about using the same technique for everyone or choosing just "one" best option. Instead, it's about "combining" (Combination Therapy) various aesthetic sciences and innovations to achieve results that are "on point" and "natural-looking" for each individual.
Imagine creating a masterpiece. A skilled artist doesn't use just one color or one brush to create a perfect piece. Instead, they choose a variety of colors, various brush sizes, and different techniques to achieve perfect detail, light and shadow, and dimension. Skin care is similar. Our skin is complex, and the problems that arise have many dimensions. True correction must delve deep into each skin layer and each problem to create "your beautiful skin" anew.
I invite everyone to understand the "solutions" we offer and how to "bundle" these approaches to maximize their benefits in reducing wrinkles, slowing down aging, and conditioning the skin at Entrio Clinic Ratchaprasong.
Group 1: "Awakening Inner Creation Power" with Biostimulators - The Foundation of Sustainable Anti-Aging
This is a truly exciting and powerful group of innovations in the aesthetic industry!
Why do I use the phrase "awakening inner creation power"? Because Biostimulators are not just about "adding" external substances into the skin for temporary results. Instead, they "signal" and "stimulate" our skin cells, especially Fibroblast cells which produce collagen and elastin, to become active again. It's like "waking up a factory" that had slowed down and making its machinery run at full capacity again to produce the essential substances the skin needs to maintain its youthfulness and health.
This mode of action makes Biostimulators the "foundation of sustainable anti-aging." Because the results come from the body producing essential substances naturally, they look very natural and last longer than merely adding external substances. At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we have carefully selected a variety of high-quality Biostimulators to effectively and precisely address different skin problems.
Let's delve into each one with me!
Sculptra: The Foundation of Volume and Structure... The Expert in Type I Collagen Production!
If your main skin problem is significant "volume loss," a hollow or tired-looking face, or "sagging" caused by the collapse of underlying skin structures, whether it's fat layers or even bone, Sculptra is a top choice and a cornerstone in laying the foundation for anti-aging!
Key Ingredient and Deep Mechanism of Action
Sculptra's key ingredient is Poly-L-Lactic Acid (PLLA), a biocompatible and biodegradable synthetic substance. When I inject Sculptra into the deep dermis or subcutaneous layer, PLLA particles act like tiny "scaffolds" that don't immediately fill but are powerful "stimulants"!
The crucial mechanism is that PLLA "stimulates Fibroblast cells," which are the main cells in the skin responsible for producing collagen and elastin, to become highly active and multiply. Most importantly, Sculptra stimulates the production of a massive amount of new "Type I Collagen"!
Type I Collagen is like the "main pillar," "support beam," and "steel frame" of the skin's building. It's the type that provides strength, density, and volume to our skin. The fact that Sculptra specifically focuses on producing this type of collagen makes it highly effective To effectively reduce wrinkles, slow down aging, and condition our skin for firmness, while still looking natural. Sculptra is often recommended for those whose main concern is significant volume loss and sagging that clearly indicates the collapse of underlying skin structures.
Key Benefits of Sculptra
Deep Collagen Stimulation: It stimulates collagen production in the deep layers of the skin, providing a strong and long-lasting foundation.
Gradual and Natural Results: The results develop gradually over a few weeks to months, making the changes appear very natural, as if your skin is naturally rejuvenating itself.
Long-Lasting: The results can last up to 2 years or even longer for some individuals, making it a highly cost-effective option in the long run.
Improved Skin Quality: In addition to volume, the new collagen also improves skin quality, making it firmer, smoother, and more elastic.
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we use Sculptra extensively in our comprehensive anti-aging programs, especially for cases requiring deep structural restoration.
Who is it suitable for?
Individuals with noticeable volume loss across the face who desire to restore a fuller, more rejuvenated appearance.
Those who wish to strengthen their skin's internal structure for long-term benefits, aiming for firmer, tighter skin and reduced laxity.
Individuals seeking very natural-looking results who are comfortable with the gradual appearance of effects (which is a long-term advantage).
Those interested in anti-aging that targets cellular and structural levels.
What you need to know: Generally, Sculptra is recommended as a course of 2-3 sessions, spaced approximately 4-6 weeks apart. It is crucial to strictly follow the doctor's instructions for post-treatment massage in the injected areas to ensure optimal PLLA distribution and maximum collagen stimulation.
Profhilo & Definisse Hydrobooster: The Experts in "Skin Quality" and "Moisture Glow"
While Sculptra focuses on deep structural volume, Profhilo and Definisse Hydrobooster address the "quality of the skin surface" and "deep hydration." If your primary concerns are dry, dull, rough skin, fine lines caused by dryness, or you desire a glowy, radiant complexion and improved elasticity, this group is the perfect fit.
Profhilo: The "Hybrid Filler" with Supreme HA Concentration for Holistic Skin Quality
Profhilo is not a traditional filler designed to add volume to specific points. Instead, it's a unique "Hybrid Filler" or a "Bio-remodeling" substance.
Key Ingredient and Deep Mechanism of Action Profhilo contains a highly concentrated form of Hyaluronic Acid (HA), up to 64 mg per 2 cc, with a unique patented manufacturing technology that combines high and low molecular weight HA without the use of chemical cross-linking agents (BDDE). This allows Profhilo to flow smoothly and diffuse widely into the skin.
When injected using specific BAP (Bio Aesthetic Points) technique (5 points on each side of the face), Profhilo diffuses widely into the dermis. Its key mechanism is to stimulate the skin cells (Fibroblasts, Keratinocytes, and Adipocytes) to produce new collagen and elastin, and improve the quality of adipose tissue (fat pads) that support the skin. It also provides deep hydration to the skin.
Impact on Skin
Profhilo significantly improves overall skin quality, making it:
Firmer and more elastic: Due to new collagen and elastin production.
Smoother: Fine lines caused by dryness are reduced.
More hydrated and radiant: Skin looks plump and glowing from within.
Overall skin health improvement: It literally remodels the skin structure.
Profhilo is suitable for
Individuals with dry, dehydrated, dull, or lackluster skin who want their skin to look healthier and more vibrant.
Those who feel their skin is starting to lose elasticity and firmness, and are beginning to notice small wrinkles across their face.
Those who want to improve overall skin quality to look healthier, plumper, and naturally glowing.
Those who want to effectively stimulate collagen and elastin in the skin layer.
Those who do not desire significant volume enhancement or drastic facial reshaping.
What you need to know: Generally, Profhilo is recommended to be administered twice, with a 1-month interval, to achieve the best results. To maintain these results, repeat treatments are suggested every 6-12 months.
Definisse Hydrobooster: The Ultimate "Hydration Booster"... For Glass Skin and Collagen Stimulation!
For those whose primary concern is "severe skin dehydration," dull and lackluster skin, fine lines caused by dryness, and a desire for "plump, dewy" glass skin, along with collagen stimulation, Definisse Hydrobooster is the perfect solution!
Key Ingredients and Mechanism of Action
Definisse Hydrobooster contains Non-Cross-linked HA (Hyaluronic Acid that is not Cross-linked) mixed with Glycerol, a substance well-known for its excellent ability to absorb and retain water in the skin. The main mechanism is to deeply hydrate the dermis, allowing the skin to be fully moisturized from within. It also helps to stimulate Fibroblast cells to produce collagen to a certain extent (as a secondary property), which strengthens the skin.
Outstanding Results
Hydrated, Radiant Skin: The most noticeable result is skin that looks plump, firm, fresh, and dewy, like "Glass Skin." Skin that is fully moisturized immediately appears more vibrant.
Smoother Skin, Finer Wrinkles Reduced: The skin's plumpness helps it appear smoother, and fine lines, especially those caused by dehydration, visibly diminish.
Slightly Firmer Skin: From both the hydration and supplementary collagen stimulation, the overall skin appears slightly firmer.
Healthier Skin Condition: Sufficiently hydrated skin leads to better cell function, making the overall skin look healthier, more radiant, and receptive to other nourishing treatments.
Suitable for whom?
Individuals with very dry, dehydrated skin that looks dull and lacks radiance.
Those with fine lines caused by skin dehydration.
Those who desire plump, dewy, "Glass Skin" appearance.
Those seeking a Skinbooster that provides ultimate hydration with supplementary collagen stimulation.
Those with dark, dehydrated under-eyes.
What you need to know: Generally, a course of treatments is recommended to maintain continuous hydration and collagen stimulation.
Juvelook: A Biostimulator Focusing on "Fine Skin Texture" and Targeted Problem Solving
For those looking for a Biostimulator that focuses on "skin conditioning," particularly concerning enlarged pores, shallow acne scars, or fine wrinkles, especially around the under-eye area, Juvelook is an interesting innovation that precisely addresses these problems!
Key Ingredients and Mechanism of Action
Juvelook is a Biostimulator that combines Poly D,L-lactic Acid (PDLLA), a derivative of PLLA (similar to Sculptra), and Non-Cross-linked Hyaluronic Acid (HA) in an optimal ratio.
The presence of HA allows Juvelook to provide a small amount of immediate filling (from HA), while the PDLLA particles gradually degrade and continuously "stimulate Fibroblast cells" to produce new collagen in the long term.
The special feature of Juvelook is the optimal particle size of PDLLA, which is suitable for injection into shallower skin layers and can effectively stimulate collagen to address delicate skin issues.
Outstanding Results in Skin Rejuvenation
Tightened Pores: New collagen production in the dermal layer around the pores strengthens and tightens the pore walls, making previously enlarged pores visibly smaller.
Filling Shallow Acne Scars: It helps replace collagen in shallow acne scars, making them appear shallower and smoother.
Reduction of Fine Wrinkles: Especially small wrinkles caused by collagen degradation in the dermis, such as under-eye wrinkles, perioral wrinkles, or other delicate facial wrinkles.
Smoother Skin Texture: New collagen production improves overall skin structure, making the skin appear finer, smoother, and of better quality.
Suitable for whom?
Individuals with enlarged pores who want to tighten their pores.
Those with shallow acne scars and who want to smooth their skin texture.
Those with fine wrinkles, especially around the under-eye area, or areas requiring precise correction.
Those who want to improve skin quality to appear finer and smoother.
What you need to know: Similar to other Biostimulators, Juvelook is often recommended as a course of treatments to ensure continuous collagen stimulation and achieve the best results.
Biostimulators... The Foundation of Youthful Skin at Entrio Clinic Ratchaprasong
All the Biostimulators I've mentioned – whether Sculptra, Profhilo, Definisse Hydrobooster, or Juvelook – are innovations that have revolutionized the beauty industry and are at the heart of a "sustainable anti-aging foundation." They don't just "hide" problems; they "correct" them at their root by "awakening your skin's inner regenerative power."
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we don't choose just one type of Biostimulator to solve all problems. Instead, my team of doctors and I specialize in "deeply assessing" your skin concerns and selecting the "most suitable" Biostimulator specifically for you. We can even "combine" treatments using multiple types of Biostimulators, or integrate them with other procedures, to achieve "comprehensive" and "holistic" results in reducing wrinkles, slowing down aging, and conditioning your skin, ultimately helping you achieve "your beautiful skin" as naturally as possible.
Group 2: "Lifting & Skin Smoothing with Energy" - The Power of Skin Remodeling
Another equally important pillar in reducing wrinkles, slowing down aging, and conditioning the skin is the innovation of energy-based devices, a field that has developed by leaps and bounds in recent years. Fundamentally, these devices use various forms of energy, whether Radiofrequency (RF) waves, Ultrasound waves, or lasers, to deliver heat or energy to different depths of the skin layers. The main goal is to stimulate the production of new collagen and elastin, causing the contraction of existing collagen fibers, resulting in visible lifting and tightening of the skin.
But what I want to emphasize today is that these devices are no longer just "lifting tools." Instead, they have evolved to a level where they can "Remodel Skin" or "restructure skin" deeply and comprehensively in many dimensions, which is extremely exciting and powerful.
Let's understand the prominent innovations in this group that we at Entrio Clinic, Ratchaprasong Aesthetic Clinic, prioritize and use in patient care.
Morpheus8: The Ultimate Radiofrequency Microneedling Innovation... The Power of Skin Remodeling from Inside Out!
If you are looking for an innovation that can lift and tighten skin while comprehensively improving skin quality to be smoother, reducing wrinkles, minimizing pores, and diminishing acne scars, Morpheus8 is the answer that Dr. Nono highly recommends and trusts! I believe Morpheus8 is an innovation that truly fills the gap in effectively addressing skin problems, and this is why it is the core of this group.
Microneedling Component (Energy from Tiny Needles) Morpheus8 uses numerous tiny gold-plated micro-pins that can be adjusted to various depths (from 0.5 mm to 8 mm, depending on the area and problem). When the needles penetrate the skin, they create "micro-injuries" or many tiny wounds in the skin, a process that triggers the body's natural "repair and regeneration process."
Radiofrequency (RF) Component (Thermal Radiofrequency Energy) This is the key differentiator of Morpheus8! After the needles penetrate the skin, Radiofrequency (RF) energy is emitted directly from the "tip of the needles," not from the external skin surface. This is very important because it means the heat energy is delivered directly to the "target"—the dermis and subcutaneous fat layers—while the outermost skin layer (Epidermis) receives minimal heat, making it safer and reducing the chance of superficial skin side effects.
Fractional RF and Subdermal Adipose Remodeling (SARD)
Fractional: The needles penetrate in tiny dots, not the entire surface, leaving normal skin surrounding the treated points, which allows for rapid recovery.
SARD (Subdermal Adipose Remodeling Device): In deeper settings (e.g., 4-8 mm for skin and excess fat concerns), Morpheus8 can deliver RF energy to the subcutaneous fat layer! This heat energy causes fat cells to "contract and remodel" (Coagulation and Remodeling) and also "stimulates new collagen production" in the fat and skin layers in that area. This property makes Morpheus8 more than just a lifting device; it can "Remodel" both skin structure and fat layers simultaneously.
Outstanding and Comprehensive Results from "Skin Remodeling" with Morpheus8
Tightening & Lifting: The deeply delivered RF energy stimulates the massive production of new collagen and elastin, strengthening the skin structure, contracting existing collagen fibers, and making the skin appear naturally tighter and lifted. This is especially suitable for those seeking to slow down aging and correct mild to moderate skin laxity.
Wrinkle Reduction: Both fine lines and deep wrinkles will noticeably diminish as the skin becomes firmer and new collagen fills in.
Texture Improvement & Pore Reduction: RF energy and Microneedling work together to stimulate new skin and collagen around the pores, making pores visibly tighter and the facial skin appear finer and smoother. This conditions the skin at a cellular level.
Acne Scar Reduction & Stretch Marks: With its ability to remodel skin structure, Morpheus8 can help improve the appearance of various types of acne scars and stretch marks, making them look shallower and smoother.
Even Skin Tone: The stimulation of new skin also promotes better cell turnover, resulting in a more even and slightly brighter overall skin tone.
Facial & Body Contouring: At appropriate depths, Morpheus8 can help reduce localized unwanted fat and tighten the skin in that area. It's suitable for reducing double chins, refining the jawline, and addressing body skin laxity.
Suitable for whom?
Those who want to lift and tighten their skin without surgery or Biostimulator injections.
Those with wrinkles, both fine and deep.
Those who want to condition their skin to be smoother, reduce pores, and diminish acne scars.
Those who want to reduce localized fat and tighten skin simultaneously (e.g., double chin, undefined jawline).
Those who seek comprehensive results for multiple skin concerns at once.
What you need to know: Generally, Morpheus8 is recommended as a course of 1-3 sessions, spaced approximately 4-6 weeks apart, depending on the individual's concerns and desired results. There might be slight redness or swelling after the procedure, but it typically subsides quickly.
Other Energy-Based Lifting Innovations: For Complete Understanding (At Entrio Clinic, we choose what's appropriate)
To give you a comprehensive overview of energy-based lifting innovations, I'd like to explain other tools you might have heard of, to compare and understand the strengths of each. At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we have a variety of tools so that our doctors can choose what is most suitable for your specific concerns.
HIFU (High-Intensity Focused Ultrasound) e.g., Ultherapy
Mechanism: Uses high-intensity, precisely focused ultrasound waves to create small heat points (Thermal Coagulation Points) in deep and specific skin layers, whether it's the deep dermis or the SMAS (Superficial Musculoaponeurotic System) layer, which is the same layer targeted in a surgical facelift.
Strengths: Focuses on lifting and reducing laxity in deep layers, providing clear results in lifting cheeks, eyebrows, reducing double chin, and naturally sharpening the jawline. Ideal for individuals with noticeable structural sagging.
Difference from Morpheus8: HIFU primarily focuses on deep structural lifting, with no impact on the superficial skin layer (Non-Invasive). It does not emphasize skin texture improvement or pore reduction like Morpheus8.
Monopolar RF e.g., Oligio
Mechanism: Uses monopolar radiofrequency (RF) energy to deliver heat uniformly into the skin (Volumetric Heating), focusing on the dermis.
Strengths: Focuses on stimulating collagen throughout the dermis, leading to the contraction of existing collagen and the creation of new collagen. This results in noticeably tighter facial and body skin, reduced wrinkles, and may help subtly sharpen the jawline.
Difference from Morpheus8: Oligio delivers energy from the external skin surface (no needles) and provides diffuse heat throughout the dermis, making it suitable for tightening skin over larger areas. Morpheus8, however, allows for more precise control over depth and energy delivery, and can also address texture issues and fat remodeling.
Dr. Nono's "Bundling Philosophy" for "Lifting & Skin Smoothing with Energy" at Entrio Clinic Ratchaprasong
I believe that choosing an energy-based device isn't just about picking the "most famous" or "newest" machine. It must be the "right" one that "addresses" the patient's actual problem. And most importantly, it must be used by a doctor with a deep understanding of the mechanism of action and the techniques for using each type of device.
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, my team of doctors and I are highly skilled in thoroughly assessing your skin concerns and will choose the most suitable energy-based device for you, whether it's Morpheus8, HIFU, or Monopolar RF. We can even "bundle" (Combination Therapy) energy-based treatments with Biostimulators or other procedures to achieve "comprehensive" and "holistic" results in reducing wrinkles, slowing down aging, and conditioning the skin, allowing you to achieve "your beautiful skin" as naturally as possible.
Skin remodeling with these energies is a worthwhile investment for strong, firm, and smooth skin in the long term. This is because it stimulates your skin to produce its own natural collagen and elastin, making the results look natural and sustainable.
Group 3: "Targeted Wrinkle Correction and Immediate Filling" - Precision and Speed in Problem Management
This group of procedures addresses the need for "speed" and "precision" in managing wrinkles caused by facial expressions or immediately restoring lost volume. While Biostimulators and energy-based devices focus on long-term skin rejuvenation and stimulating regeneration from within, certain injectables remain essential and highly effective tools for targeted problems requiring quick results to make the face look younger and brighter instantly.
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we choose standardized, safe products administered by expert doctors to ensure the most natural and beautiful results.
Let's take a look at the key tools in this group.
Botulinum Toxin (Botox): The Expert in "Reducing Dynamic Wrinkles"
If you're concerned about wrinkles that appear when you smile, frown, or raise your eyebrows—these are Dynamic Wrinkles—then Botulinum Toxin is the hero for this problem!
Precise Mechanism of Action Botulinum Toxin is a purified protein that works by inhibiting the function of acetylcholine, a neurotransmitter that sends signals from nerves to muscles. When a doctor injects the appropriate amount of Botulinum Toxin into the target muscle, that muscle temporarily relaxes and cannot contract. This muscle relaxation causes wrinkles resulting from repeated muscle contractions (e.g., forehead wrinkles, crow's feet, frown lines) to temporarily fade or disappear, making the skin in that area appear smoother.
Outstanding Results in Wrinkle Reduction
Reduces forehead wrinkles, frown lines (the "11" lines), and crow's feet: This is the strongest point of Botulinum Toxin injections. These wrinkles will visibly diminish or disappear, making the face look naturally younger and smoother.
Prevents permanent wrinkles: Early Botulinum Toxin injections, when wrinkles are not yet deep, can help prevent these lines from developing into permanent deep wrinkles (Static Wrinkles).
Facial Contouring and Other Applications (Secondary Benefits) In addition to wrinkles, Botulinum Toxin can also be used for certain facial contouring procedures, such as:
Masseter reduction: Makes the face appear slimmer (V-shape).
Lifting downturned mouth corners: Helps the face look more cheerful and bright.
Nasal flare reduction: Makes the nose appear slimmer.
Reducing underarm/palm/foot sweating: Addresses excessive sweating (hyperhidrosis).
Improving undefined jawline (Platysmal Band): Helps to sharpen the jawline.
Onset and Duration of Results
Onset: Results typically begin to appear in 3-7 days and reach full effect in 2 weeks.
Duration: Results usually last about 3-6 months, depending on the brand, injected amount, and individual response.
What to Know
Importance of an experienced doctor: Botulinum Toxin injections require high precision in terms of injection location, appropriate dosage, and injection technique to achieve natural-looking results without a frozen appearance and to avoid undesirable side effects. At Entrio Clinic Ratchaprasong, my team of doctors and I have deep experience and understanding of facial anatomy to ensure you receive the best and safest results.
Botulinum Toxin cannot completely correct deep, permanent wrinkles (Static Wrinkles) that are present even without facial expressions. These types of wrinkles often require Dermal Fillers or other treatments in combination.
Using genuine and standardized Botulinum Toxin products is extremely important.
Dermal Fillers ("Filler"): The Immediate Solution for Wrinkles and Volume Loss!
If your problem is deep static wrinkles that are clearly visible even without facial expressions, or volume loss in various areas of the face that makes your face look tired, drawn, and you want "immediate" results, Dermal Fillers are the precise answer!
Key Ingredient and Mechanism of Action: Hyaluronic Acid (HA)... Filling for Youthful Dimensions
Most Dermal Fillers used today are made of Hyaluronic Acid (HA), a substance naturally produced by our bodies. HA has excellent water-binding properties and is a key component of skin and connective tissue.
The HA used in fillers is synthesized and undergoes a "Cross-linking" process, which links HA molecules to form a gel with increased viscosity and longer-lasting stability. The difference in this Cross-linking process is what gives fillers varying properties in terms of softness, firmness, and ability to maintain shape.
When a doctor injects filler into the appropriate skin layer (deep dermis, subcutaneous tissue, or even above the bone), the HA gel directly "fills the missing space," making the skin in that area appear fuller, plumper, and deep wrinkles immediately shallower.
Outstanding Results in Filling and Facial Contouring
Fills deep static wrinkles: Reduces the appearance of various wrinkles that are always present, such as nasolabial folds (laugh lines), marionette lines, and fine perioral lines.
Restores lost volume: Fills in hollows in various areas caused by fat and bone resorption, making the face look fuller and younger, such as:
Under-eyes (Tear Troughs): Corrects hollow, dark under-eyes that make one look tired.
Sunken temples: Makes the face appear more harmonious and youthful.
Hollow cheeks: Restores plumpness to the face, making it look brighter.
Chin and jawline: Sculpts the face for better proportions and definition.
Facial Contouring & Enhancement:
Lips: Adds volume, sharpens lip borders, or reshapes for a more beautiful appearance.
Nose: Enhances the nasal bridge or subtly corrects shape (Non-surgical Nose Job).
Cheekbones: Adds dimension to the face for a more structured look.
Skin Quality Improvement: Some types of fillers (e.g., Skinboosters) with non-cross-linked HA focus on hydrating and improving overall skin quality, making the skin appear plumper and smoother (which may overlap with some Biostimulators we've already discussed).
Onset and Duration of Results:
Onset: Results are visible immediately after the procedure.
Duration: Generally lasts 6-18 months or longer, depending on the type of filler, the injected area, muscle movement in that area, and individual lifestyle.
What to Know:
Importance of an experienced doctor and expertise: Filler injection requires precise anatomical knowledge, experience, and, importantly, an "artistic eye" to achieve natural-looking results that harmonize with the face, without appearing stiff or overfilled. At Entrio Clinic Ratchaprasong, I emphasize meticulous and detailed filler injection to create beautiful results that blend seamlessly with your facial features.
Genuine and safe products: Choosing genuine, FDA-approved, and standardized fillers is extremely important for maximum safety and confidence in the effectiveness and duration of the results.
While results are quick, fillers do not sustainably stimulate collagen production like Biostimulators (with the exception of some types that have Biostimulator properties themselves).
Dr. Nono's "Bundling Philosophy" at Entrio Clinic Ratchaprasong: Because the Best Results Begin with True Understanding
As I have consistently emphasized, everyone's skin is complex, and aging is a process caused by multiple factors simultaneously. Therefore, the most comprehensive and sustainable solution to skin problems requires the intelligent "bundling" and "combination" of various methods.
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, we are proud to present this concept through meticulous and attentive care:
Precise Assessment
We don't just look at superficial skin problems. Instead, I meticulously assess your facial structure, from bone, fat layers, and muscles to the condition of each skin layer. We utilize skin analysis tools and the doctor's experience to understand the "root cause" of your concerns and your true "expectations."
This assessment is the cornerstone for designing a "Personalized Treatment Plan" that is precisely "right" for you alone.
Selection of Diverse and Standardized Technologies
We carefully select only Biostimulator products and energy-based devices that are internationally recognized, research-backed, and highly safe. Whether it's Sculptra, Profhilo, Definisse Hydrobooster, Juvelook, Morpheus8, or others, we have a comprehensive "toolbox" to ensure we can choose what is most suitable for your specific problem.
The Art of Combination Therapy
This is a key strength of Entrio Clinic Ratchaprasong. We understand the unique properties and limitations of each procedure and can "bundle" them seamlessly to create a synergistic effect that comprehensively addresses problems across all dimensions.
Examples of "Bundling" in Practice
For Volume Loss + Dull Skin Quality: Start with Sculptra to build volume and reinforce core structures, then perhaps follow with Profhilo to rejuvenate overall skin quality for a plump, hydrated, and glowing complexion.
For Laxity + Uneven Skin Texture + Wrinkles: Use Morpheus8 for lifting, skin conditioning, wrinkle reduction, and pore tightening, in conjunction with Botulinum Toxin to reduce dynamic expression lines in specific areas.
For Dry Skin + Fine Wrinkles + Desire for Collagen Stimulation: Use Definisse Hydrobooster for ultimate hydration, and potentially supplement with Morpheus8 at appropriate energy levels to stimulate collagen and improve overall skin condition, or use Juvelook in areas requiring precision, such as under the eyes.
For Comprehensive Facial Rejuvenation (Ultimate Rejuvenation): We may use a Biostimulator (e.g., Sculptra) as a foundation for building volume and structure, followed by an Energy-Based Device (e.g., Morpheus8) to improve texture and tightening, complemented by Fillers for filling deep lines and Botulinum Toxin for specific wrinkles, along with continuous use of appropriate skincare.
Natural and Sustainable Results
Our ultimate goal is to rejuvenate and improve your skin quality to look naturally better, not to make you look "changed" or "fake." We focus on results that make you look brighter in a way that is authentically you and that last longer by stimulating your body's natural mechanisms.
Why Entrio Clinic, Ratchaprasong Aesthetic Clinic, is the Best Choice for You:
Leading Experienced Doctors: I, Dr. Chanapat Chinvejkijwanich, Medical License No. 60686, and the Entrio Clinic medical team possess deep experience and understanding in skincare, with expertise in various techniques and continuous updates on new knowledge.
World-Class Products and Technology: We meticulously select only genuine Biostimulator products and the most advanced energy-based devices that have received international certification, ensuring maximum safety and efficacy for our patients.
Heartfelt Service in a Superior Atmosphere: At Entrio Clinic Ratchaprasong, we are committed to providing you with a "Refined Aesthetic Experience," featuring a luxurious, relaxing atmosphere and attentive service in every detail, from the moment you step in.
Prime City Center Location: Being located in the Ratchaprasong area makes our clinic easily accessible, whether by BTS Skytrain or private transport, suiting the urban lifestyle.
Your First Step to "Your Beautiful Skin" Starts at Entrio Clinic Ratchaprasong!
Don't let the "signs of aging" undermine your confidence any longer. The best skincare begins with a thorough understanding of the problem and choosing the most appropriate "solution."
I invite everyone who is looking for a Ratchaprasong Aesthetic Clinic that deeply understands your skin concerns and is ready to design the "right" treatment plan to reduce wrinkles, slow down aging, and condition your skin to look as good as you desire... come consult me at Entrio Clinic Ratchaprasong.
My team and I are ready to take care of you every step of the way, so you can rediscover "your beautiful skin" looking bright, radiant, and naturally youthful once again.
Entrio Clinic - Refined Aesthetic Experience
"We believe that true beauty comes from good skin health and an understanding of science."
📍 Location: https://maps.app.goo.gl/X9WpN51pnK5otKip8
4th Floor, Erawan Bangkok Building, Ratchaprasong Intersection (behind the Erawan Shrine), Bangkok.
💬 Line: @entrioclinic or click bit.ly/EntrioLine
📞 Tel: 097-154-2222
🌐 Website: entrioclinic.com
💻 Facebook: facebook.com/EntrioClinic
📷 Instagram: entrioclinic or click instagram.com/entrioclinic/
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