From Dr. Nono's Experience: How to Effectively Treat "Acne Scars" and "Wrinkles"... with a Vision for "Skin Remodeling" at Entrio Clinic
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Hello everyone! I'm Dr. Nono, Dr. Chanapat Chinwachakitwanich, License No. 60686, owner of Entrio Clinic, an aesthetic medical clinic in the heart of Ratchaprasong!
As a physician who has been deeply involved in the beauty and anti-aging medicine industry for a long time, I have met and cared for many patients who are constantly concerned about skin problems that undermine their confidence. Two major problems that I frequently receive consultations for, and which pose a continuous "big challenge" to the beauty industry, are "acne scars" and "wrinkles"!
Many of you may have tried various methods, used many skincare brands, or undergone several types of procedures, but still haven't seen satisfying results, have you?
This is because "acne scars" and "wrinkles" are not superficial skin problems that can be solved with simple methods. They are "signals" indicating changes occurring in the deeper layers of our skin, which require deep understanding and "targeted" and "comprehensive" treatment.
I will reveal secrets from my own experience regarding the concepts and "solutions" we offer at Entrio Clinic, Ratchaprasong Aesthetic Clinic, to effectively manage "acne scars" and "wrinkles" so that you can truly achieve the smooth, radiant, and youthful skin you desire.
Understanding "Acne Scars" and "Wrinkles": The Root Causes We Must Address Thoroughly
I always begin treatment by understanding the "root cause" of these problems. It's like investigating a case, where we must find the "cause" and the true "perpetrator" to lead to a targeted and sustainable solution.
Two main problems that often concern many patients and lead them to consult me frequently are "acne scars" and "wrinkles"!
Although both problems appear on the face, their origins and mechanisms are entirely different. This means that "treatment methods" must also differ. I will take you on a deep dive to "understand" the essence of these problems so that you are well-informed and can wisely decide on the appropriate treatment approach for yourself.
1. "Acne Scars": Unwanted Scars of Memory... Deep-seated Skin Damage
I want everyone to understand that acne scars are not just "holes" in the skin. They are actually a type of permanent "scar" on our skin and a clear sign that the tissue in our dermal layer was severely damaged in the past.
Mechanism of Acne Scar Formation: A Tragic Sequence of Events Beneath the Skin
The formation of acne scars is a complex and fascinating process in skin pathophysiology. It usually results from severe inflammatory acne, especially nodules, cysts, or large, deep, widespread inflammatory acne, which differs from ordinary inflammatory acne that does not leave permanent scars.
Severe and Deep Inflammation When severe inflammatory acne occurs, the Propionibacterium acnes (P.acnes) bacteria living in the hair follicles multiply and combine with clogged sebum and dead skin cells, causing significant inflammation. The body's immune system responds by sending white blood cells and various chemicals to eliminate pathogens and damaged cell debris. This process leads to the swelling, redness, heat, and pain we see on the skin. In severe inflammatory acne, the inflammation spreads from the hair follicle to destroy the follicle wall and expands widely into the deep dermal layer, and may even go as deep as the subcutaneous layer.
Irreversible Collagen & Elastin Destruction During severe inflammation, white blood cells and other inflammation-related cells release various enzymes, especially the Matrix Metalloproteinases (MMPs) group. These enzymes naturally break down old tissue to make way for new tissue to form. However, in cases of severe inflammatory acne, MMPs are excessively and prolonged activated, causing them to attack and "destroy" collagen and elastin fibers, which are the main structures supporting smooth, strong, and elastic skin, permanently and severely. This destruction is not just "digesting" old tissue but a "tearing" and "loss" of a large amount of collagen tissue, causing gaps and irreversible damage to the underlying skin structure that cannot return to normal on its own.
Incomplete or Abnormal Wound Healing Process When acne inflammation subsides, the body tries to repair the damaged areas, which is a natural process of wound healing. However, in the case of acne scars, this repair is often "incomplete" or "abnormal":
Insufficient Collagen Production: Sometimes the body cannot produce enough new collagen to replace all the destroyed parts, leading to "gaps" or "indentations" in the tissue.
Abnormal New Collagen Arrangement: The newly formed collagen (especially Type III collagen, which is abundant in the early stages of wound healing) may have an irregular arrangement or the formation of "fibrous tissue" beneath the skin.
Fibrous Tethering: In some types of acne scars, particularly Rolling Scars, fibrous bands formed during abnormal wound healing "pull" the dermis to attach to the fat layer or underlying subcutaneous tissue. This causes the skin in that area to be pulled down, creating deep, wave-like indentations on the skin.
Understanding this complex process makes us realize that acne scars are not just superficial skin problems that can be solved with skincare alone. Instead, they are structural damage that requires external intervention to stimulate new tissue formation and reorganize the damaged structure.
Types of Acne Scars: Why Classification is Crucial for Treatment!
As a physician, I place great importance on "diagnosing" the type of acne scar because each type has different "physical characteristics" and "subcutaneous structures" , which leads to choosing the most "targeted" and "effective" treatment. Incorrect treatment will not only be ineffective but may also waste time and money unnecessarily.
Ice Pick Scars (Pitted Scars or Pick Scars)
Imagine a hole made by driving a small nail deep into wood—that's an Ice Pick Scar. It's a small but very deep hole with strong edges.
Characteristics: These are very small scars (less than 2 millimeters) with narrow, sharp openings but are very deep, resembling a puncture or incision made by a sharp object. The base of the scar tapers to a "V" shape or a narrow, deep cone.
Depth: They can extend into the deep dermal layer and potentially into the subcutaneous layer.
Commonly Found: Often seen on the cheeks and forehead, areas with oiliness and relatively small pores.
Problems and Treatment Challenges: Due to the narrow and deep opening, stimulating collagen from the surface (e.g., general lasers or Derma Roller) is difficult because the energy cannot reach the bottom of the scar, and the surrounding tissue remains intact. Treating this type of scar often requires methods that focus on destroying the scar wall or directly stimulating tissue formation from the bottom of the scar, such as TCA Cross, Punch Excision, or using Morpheus8, which can deliver deep energy and destroy the scar wall.
Boxcar Scars (Box-like Scars)
Like a well with clear, defined walls and a flat bottom. Filling the well is the main approach.
Characteristics: These are round or oval-shaped scars ranging from 2-4 millimeters or larger, with clear edges perpendicular to the skin, resembling a well or scars from chickenpox. The base of the scar is flat, and the difference in depth from normal skin is clearly visible.
Depth: Can vary in depth from shallow to very deep.
Commonly Found: Often seen on the cheeks and temples.
Problems and Treatment Challenges: The clear edges and tissue depression require collagen stimulation to fill the base of the scar and elevate the scar walls to make the skin appear smoother. This type of scar usually responds well to collagen stimulation with energy-based devices (e.g., Morpheus8, Fractional Laser ) or Biostimulators (e.g., Juvelook) which help fill tissue from below
Rolling Scars (Wave-like Scars or Undulating Scars)
Like a tablecloth being pulled down by hooks from below, creating wave-like wrinkles on the surface. To smooth the cloth, those hooks must first be released.
Characteristics: These are shallow, wide indentations, typically larger than 4 millimeters, with no clear edges. Instead, they appear as widespread depressions of the subcutaneous tissue, making the skin look uneven, like rolling waves or undulating surfaces.
Depth: Often not very deep compared to Ice Pick scars but cover a wide area, and the depression is caused by fibrous tethering.
Main Cause: Caused by fibrous bands formed from abnormal wound healing in the deep dermal layer, which "pull" the dermis to attach to the subcutaneous fat layer. This causes the skin in that area to be pulled down, creating wave-like indentations on the skin.
Commonly Found: Often seen on the cheeks and temples, areas with high skin elasticity.
Problems and Treatment Challenges: The primary step in treating this type of scar is to "break" or "cut" the fibrous bands that are pulling the skin down, allowing the skin to lift. This is followed by collagen stimulation to fill and reorganize the skin structure for a smoother appearance. Subcision is often a crucial step in treating Rolling Scars, alongside the use of Morpheus8 or Biostimulators.
Accurate diagnosis of acne scar types is therefore an extremely important first step in treatment planning at Entrio Clinic, Ratchaprasong Aesthetic Clinic , because the "Skin Remodeling" methods will vary according to the characteristics of each scar type. This deep understanding of the "root causes" of acne scars is what allows us to design "targeted" and "satisfying" treatments for our patients.
2. "Wrinkles": The Path of Time and Behavior... Changes in Every Skin Layer
I always emphasize that to effectively solve skin problems, we must thoroughly understand their "root causes." If we only see the "symptoms" on the face but don't know the true underlying cause, it's like trying to repair a house without knowing which structural parts are damaged.
I will take you on a deep dive into one of the top skin concerns for many patients: "wrinkles"! Although we see wrinkles as just fine lines on the skin, they are actually signs of changes occurring in every layer of the skin, from the outermost layer to the underlying bone structure. This is a complex process influenced by many factors.
Wrinkles are not just fine lines visible to the naked eye. They are signs of changes occurring in every layer of the skin, from the outermost layer (Epidermis) down to the dermis, the subcutaneous layer (Subcutis or fat), and even changes in the facial bone structure. Understanding this complex dimension is key to effectively and sustainably managing wrinkles.
Detailed Mechanism of Wrinkle Formation (Multi-factorial Aging)
Wrinkle formation is a complex process and a combination of many factors. We can divide these factors into two main groups:
Intrinsic Aging / Chronological Aging: This is natural aging caused by genetic and biological changes within the body, which is unavoidable but can be slowed down.
Extrinsic Aging: This is aging caused by environmental effects and lifestyle habits, which we can control and prevent.
Let's delve into each factor:
Collagen & Elastin Degradation and Reduction:
Collagen & Elastin Degradation and Reduction Collagen: Like the "main pillars," "structure," and "foundation" of the skin. Collagen is a fibrous protein that provides strength, firmness, and a stable structure to our skin. The most abundant collagen in the skin is Type I collagen, which provides strength and density, and Type III collagen, which provides elasticity and is abundant in young skin.
Elastin: Like "springs" or "rubber bands" that provide elasticity and the ability of the skin to return to its original shape. When skin is stretched or compressed, elastin helps it spring back.
Aging Process:
Decreased Production: Naturally, after approximately 20-25 years of age, our bodies begin to produce less collagen and elastin, about 1% per year or more. This means that every year, our skin gradually loses important substances that keep it youthful.
Increased Breakdown: At the same time, the breakdown rate of existing collagen and elastin increases. Certain enzymes break down these structures.
Result: When collagen and elastin decrease and degrade, our skin begins to lose strength, density, and elasticity, making it thinner, less firm, and when the skin is repeatedly folded or wrinkled, "folds" that cannot fully relax occur, becoming clearly visible "wrinkles."
Volume Loss & Bone Resorption:
Volume Loss & Bone Resorption Subcutaneous Fat Atrophy and Redistribution: The subcutaneous fat layer acts as a "cushion" and provides "volume" to the face, making the face look plump and youthful. As we age, subcutaneous fat does not decrease uniformly in all areas; instead, it undergoes atrophy and redistribution downwards due to gravity.
Atrophy: Some fat significantly decreases in certain areas, such as the temples, under the eyes, cheeks, or around the mouth, making the face look hollow, tired, and deepening existing lines.
Redistribution: Fat that was once higher up may move downwards, accumulating in the lower part of the face, leading to sagging cheeks, deeper nasolabial folds, marionette lines, and jowls.
Bone Resorption: This is something many people may not know: our facial bone structure also changes and atrophies with age. Bones undergo resorption in certain areas, such as:
Around the Eyes: The bones around the eye sockets widen and deepen, making the eyes look hollow and deepening under-eye hollows.
Jawline: The jaw and chin bones resorb, making the jawline less defined and the chin appear shorter.
Cheekbones: Cheekbone resorption causes the midface to flatten and the cheeks to sag.
Result: The loss of volume from both fat and bone layers makes the overall face appear deteriorated, sunken, tired, older than its age, and importantly, "emphasizes" existing wrinkles, making them appear clearer and deeper.
Photoaging & Environmental Damage:
Photoaging & Environmental Damage UV Radiation from Sunlight: Sunlight is the number one "arch-enemy" of the skin and the most significant factor accelerating wrinkle formation. UV radiation (especially UVA and UVB) damages DNA in skin cells and stimulates the production of a huge number of free radicals. These free radicals severely and permanently attack and destroy collagen and elastin fibers.
Results from UV Radiation: Leads to a condition called "Elastosis," which is the abnormal arrangement, thickening, and degradation of elastin fibers. This results in rough skin, loss of elasticity, a yellowish-dull complexion, and deep, stubborn wrinkles (Solar Elastosis). It also causes melasma, freckles, dark spots, and increases the risk of skin cancer.
Pollution: Small particles in pollution, especially PM 2.5, can easily penetrate the skin, create free radicals, stimulate inflammation, and disrupt the skin's protective barrier. All of these accelerate the breakdown of collagen and elastin, leading to wrinkles and premature skin aging.
Overall Result: Continuous exposure to sunlight and pollution without protection causes the skin to age faster than its actual age. The skin will look dull, rough, and wrinkles will appear more clearly and rapidly.
Repetitive Facial Expressions:
Repetitive Facial Expressions Dynamic Wrinkles: These wrinkles occur when we use facial muscles for various expressions, such as smiling (leading to crow's feet), frowning (leading to frown lines or "11" lines), raising eyebrows (leading to forehead wrinkles), squinting (leading to wrinkles around the eyes). These wrinkles appear when muscles are active and disappear when muscles relax when we are young and our skin is still elastic.
Static Wrinkles: This is the real problem! As we age and the skin continuously loses collagen and elastin (as per factor 1), these facial expression wrinkles, which used to disappear when muscles relaxed, begin to "embed deeply" and "appear all the time," even when we are not making expressions.
Result: The progression of Dynamic Wrinkles to Static Wrinkles is a sign of permanent skin degradation that requires intervention.
Lifestyle Factors & Genetics:
Lifestyle Factors & Genetics Smoking: A major culprit that severely damages collagen and elastin, making the skin look dull, with deep wrinkles, and noticeably older than its age.
Inadequate Nutrition: Lack of essential nutrients for collagen production (e.g., Vitamin C, protein) or excessive sugar consumption (Glycation, a reaction where sugar binds to proteins in the body, making collagen and elastin stiff and dysfunctional) also accelerates wrinkle formation.
Insufficient Sleep, Chronic Stress, Dehydration: These all affect the repair and rejuvenation processes of skin cells, making the skin look tired, dull, and prone to wrinkles.
Genetics: Some people may have genetics that cause their skin to age faster or slower than others, such as producing less collagen or having more collagen-destroying enzymes. This is a factor we cannot control, but we can slow down the changes with proper care.
I hope this detailed and in-depth information about "wrinkles" helps you gain a greater understanding that wrinkles are not just lines on the skin, but the result of complex changes in every structural layer of the skin. Understanding the root causes of each type of wrinkle will be key to choosing "targeted" and "combined" treatment methods to achieve the smoothest, most youthful, and natural results.
From Dr. Nono's Experience: "Solutions" for "Acne Scars" and "Wrinkles" at Entrio Clinic Ratchaprasong... Emphasizing Intelligent "Skin Remodeling"!
Now that we have thoroughly delved into the "root causes" and "mechanisms" of "acne scars" and "wrinkles" , I hope you have a clearer picture that these skin problems are not merely superficial but are the result of complex changes in every layer of the skin and facial structure.
We will now move to the core of this article: the "solutions" that Entrio Clinic, Ratchaprasong Aesthetic Clinic, offers for these problems. From my experience, I am confident that treating "acne scars" and "wrinkles" to achieve satisfying and sustainable results cannot be done with a single method. Instead, it requires a concept called "Combination Therapy," and the crucial heart of this concept is intelligent "Skin Remodeling"!
"Skin Remodeling" means adjusting damaged skin structures to become strong, organized, and function better again. It's like restoring an old, dilapidated building to become beautiful, strong, and even more functional than before.
Let's see what "tools" we have at Entrio Clinic Ratchaprasong and how we use them to manage "acne scars" and "wrinkles" for the best results.
From Dr. Nono's Experience: "Solutions" for "Acne Scars"... Emphasizing Intelligent Stimulation of New Tissue Formation and Collagen Organization!
Treating "acne scars" is one of the greatest challenges in dermatology. This is because we are correcting existing "scars," which means that a part of the tissue has disappeared or the collagen arrangement has permanently become abnormal. Therefore, our primary goal is to stimulate the sufficient production of new collagen and tissue, and importantly, to organize that collagen neatly to make the "hollows" shallower and the skin appear as smooth as possible naturally. At Entrio Clinic, we have a variety of treatment approaches that are strategically combined according to the type of scar and the severity of the problem.
Morpheus8: The Key to "Skin Remodeling" and Deep Acne Scar Management!
If I had to choose an innovation that can "Remodel Skin" and comprehensively and deeply manage acne scar problems today, I would undoubtedly pick Morpheus8 as one of the top choices!
Intelligent Mechanism: Fractional RF Microneedling with Structural Reorganization Energy!
Microneedling Component (Energy from Micro-needles): Morpheus8 uses numerous specially designed tiny gold micro-pins. These needles can adjust the depth of penetration into the skin at various levels (from 0.5 mm for superficial skin to 8 mm for deeper skin problems or subcutaneous fat). The penetration of the needles into the skin creates countless tiny "Micro-injuries" or small wounds on the skin, a process that "stimulates" the body to initiate a "process of wound healing and tissue repair." This process will naturally lead to the production of new collagen and elastin in the skin.
Fractional RF (Radiofrequency) Energy Component: This is the most crucial part! Morpheus8 delivers concentrated RF energy through the tips of these micro-needles, directly into the deep dermal layer (and potentially subcutaneous fat).
Collagen Contraction and Reorganization: RF energy generates heat, causing immediate contraction of existing collagen fibers (leading to immediate skin tightening) and stimulating fibroblasts (cells responsible for producing collagen and elastin) to produce new collagen and elastin more effectively and continuously.
Deep and Controlled Heating: The fractional nature means the energy is delivered in a precise, controlled pattern, creating microscopic thermal zones. This allows for effective deep heating while minimizing damage to the surrounding healthy tissue, leading to faster recovery and less downtime.
Destruction of Fibrous Bands: For acne scars, especially Rolling Scars, the deep RF energy can help destroy the fibrous bands that pull the skin down, releasing the tethers and allowing the skin to lift and smooth out.
Overall Effect: "Skin Remodeling" from the Deepest Layers! Morpheus8 is not just about stimulating collagen on the surface; it's about "remodeling" the entire skin structure from the inside out. It acts on multiple layers simultaneously:
Epidermis: Improves texture, reduces pore size, and evens skin tone.
Dermis: Significantly stimulates new collagen (Type I and III) and elastin, improving skin density, firmness, and elasticity, thereby effectively treating acne scars and fine lines/wrinkles.
Subcutaneous Fat (when using deeper settings): Can target and remodel fat tissue, which is beneficial for certain types of acne scars or for facial contouring.
"For me, Morpheus8 is like a smart 'structural engineer.' It goes in to 'demolish' the fibrous bands that pull acne scars down, and simultaneously 'reinforces' new collagen structures strongly in the damaged skin layer. This makes the 'pits' that were once deep gradually shallower, and the surface of the face returns to being smooth with quality."
Biostimulators (Collagen Stimulators) for Acne Scars: Filling Tissue from the Inside Out!
Even though Morpheus8 is powerful, in some cases, especially for very deep acne scars, widespread tissue depression, or when significant volume restoration is needed, Biostimulators are another important tool to enhance the results.
Juvelook
Juvelook Role: I often use Juvelook to treat shallow acne scars, especially shallow Boxcar scars or Rolling Scars that are not very deep, as well as to improve large pores and overall skin quality.
Mechanism: Juvelook's main ingredients are Poly D, L-Lactic Acid (PDLLA) micro-particles and Non-cross-linked Hyaluronic Acid (HA). When injected into the skin, HA immediately provides hydration and volume. More importantly, PDLLA gradually breaks down while continuously stimulating fibroblast cells to produce new collagen around the PDLLA particles over the long term. This makes the skin firmer, shallow acne scars shallower, pores tighter, and the skin appear smoother and more refined.
Sculptra
Sculptra Role: For cases with very deep acne scars and clear tissue depression in the cheek area, or widespread Volume Loss, I may consider using Sculptra in appropriate amounts.
Mechanism: Sculptra's active ingredient is Poly-L-Lactic Acid (PLLA), which consists of small particles that, when injected into the subcutaneous layer, stimulate fibroblast cells to produce a massive amount of new Type I collagen (the main collagen providing strength and density to the skin) naturally. This process gradually creates volume and fills in missing tissue, making deep acne scars shallower sustainably and the skin appear lifted from within.
Supplemental Treatments for Acne Scars (for maximum results)
The most effective treatment for acne scars often requires a combination of methods.
Subcision (Subcision)
Role: This is a crucial procedure for Rolling Scars with clear fibrous tethering.
Mechanism: The doctor uses a special sharp-tipped needle inserted under the skin in the scarred area to "cut" or "release" the fibrous bands pulling the skin down. This releases the tethered skin, allowing the area to lift and creating a space under the scar that can better receive stimulation for new collagen formation.
Combination: Often performed in conjunction with injecting Biostimulators (e.g., Juvelook, Sculptra) or performing Morpheus8 to allow new collagen to fill the space created by subcision.
TCA Cross (TCA Cross)
Role: Specifically for deep and narrow Ice Pick Scars.
Mechanism: The doctor carefully applies high-concentration Trichloroacetic Acid (TCA) (usually 70-100%) precisely into each individual acne pit. The acid specifically destroys the side walls of the scar and stimulates collagen formation from the bottom of the pit to fill it in and make it shallower.
Limitations: Must be performed by a highly specialized physician and often requires multiple sessions.
Medical-grade Skincare (Continuous Skincare)
Even though procedures address structural problems, proper skincare is essential.
Role: Skincare containing ingredients like Retinoids (e.g., Retinol, Tretinoin), Growth Factors, or Peptides that stimulate collagen production and cell turnover will enhance treatment results and help prevent new acne and new scars in the long term.
Sunscreen Use: Prevents old scars from darkening and helps prevent new acne.
From Dr. Nono's Experience: "Solutions" for "Wrinkles"... Emphasizing Skin Structure Restoration, Movement Control, and...
Just as we thoroughly analyzed the "root causes" and "mechanisms" of "wrinkles" previously, the key to effective and sustainable treatment lies in addressing all aspects of the problem. At Entrio Clinic, Ratchaprasong Aesthetic Clinic, our approach to managing wrinkles is not merely to "fill" them superficially, but to "remodel" the skin's structure from within by stimulating collagen production, restoring lost volume, controlling muscle movements that create dynamic wrinkles, and protecting the skin from external damage.
Let's look at the "tools" and "methods" we use to manage "wrinkles" effectively:
Botulinum Toxin (Botox/Dysport/Xeomin): The Key to Dynamic Wrinkles and Prevention!
When it comes to wrinkles, especially those that appear when we make facial expressions, Botulinum Toxin, or "Botox" as it's commonly known, is an indispensable tool!
Role: Primarily used to treat Dynamic Wrinkles (wrinkles that appear when facial muscles are active) and also to prevent these wrinkles from becoming permanent Static Wrinkles. It can also be used to slim the jawline or reduce sweating.
Mechanism: Botulinum Toxin is a neurotoxin protein that works by temporarily blocking nerve signals to the muscles that cause wrinkles. When the muscles relax, the skin above them smooths out, making existing wrinkles less visible and preventing new wrinkles from forming due to repetitive muscle contractions.
Targeted Areas: Commonly used for crow's feet around the eyes, frown lines between the eyebrows (the "11" lines), and forehead wrinkles.
Result: After injection, wrinkles gradually smooth out within a few days to a week. The effect typically lasts for 3-6 months, after which muscle movement gradually returns, and the treatment can be repeated.
Important Note: To achieve natural-looking results without a "frozen" face, it requires a physician with expertise in facial anatomy and precise injection techniques.
Hyaluronic Acid Filler: Immediate Volume Restoration and Deep Wrinkle Filling!
Filler, especially Hyaluronic Acid (HA) filler, is another important "tool" that addresses wrinkles by directly restoring lost volume and filling in deep lines.
Role: Primarily used to treat Static Wrinkles (wrinkles that are visible even when not making expressions) and to restore lost facial volume due to aging, fat atrophy, and bone resorption.
Mechanism: HA is a natural substance found in our skin. HA filler is a gel-like substance that, when injected, immediately adds volume to the treated area. Different types of HA fillers have varying molecular sizes and cross-linking, allowing them to be used for different purposes, from filling fine lines to creating volume in deeper layers.
When Injected: The HA gel directly "fills the missing space" in the appropriate skin layer (deep dermis, subcutaneous layer, or even above the bone), making the skin in that area appear plumper, firmer, and deep lines shallower immediately.
Outstanding Results in Filling and Contouring:
Fills Deep Static Wrinkles: Reduces the appearance of wrinkles that are constantly present, such as nasolabial folds, marionette lines, or fine lines around the mouth (perioral lines).
Restores Lost Volume: Fills in depressions in various areas caused by fat and bone resorption, making the face look fuller and more youthful, such as hollow under-eyes (tear troughs), sunken temples, hollow cheeks, or creating a sharper, more proportionate jawline and chin.
Facial Contouring & Enhancement: Adds volume to lips, slightly enhances the nose bridge (non-surgical nose job), adds dimension to cheekbones.
"If your face is like a cloth that has been wrinkled and dented by gravity and time, filler is like 'tightening' and 'filling' the sunken parts immediately, making the cloth smooth again and beautifully dimensional."
Biostimulators (Collagen Stimulators) for Wrinkles and Anti-Aging: Skin Structure Restoration from the Inside Out!
Although they don't provide results as quickly as fillers, Biostimulators are the true heart of anti-aging and treating wrinkles at their root cause. They are an investment in strong, youthful skin for the long term.
Sculptra (Sculptra)
Role: For wrinkles caused by severe Volume Loss and sagging facial structure, including deep lines resulting from widespread collagen degradation.
Mechanism: Sculptra contains Poly-L-Lactic Acid (PLLA), which consists of small particles that, when injected into the subcutaneous layer, stimulate fibroblast cells to produce a massive amount of new Type I collagen (the main collagen providing strength and density to the skin) naturally. This process gradually creates volume and fills in missing tissue, making the face appear lifted and wrinkles shallower naturally.
Result: Gradual and natural improvement over several months, with results lasting up to 2 years or more. It addresses the underlying cause of aging by building the skin's own collagen.
Profhilo (Profhilo)
Role: For overall skin quality improvement, especially for fine lines, dehydration, and mild laxity across the face and neck.
Mechanism: Composed of a high concentration of high and low molecular weight HA, linked by thermal bonding. It doesn't act as a filler for volume but spreads naturally within the skin to stimulate fibroblasts to produce new collagen, elastin, and the body's own HA. This leads to deep hydration, improved elasticity, and a subtle lifting effect.
Result: Improved skin texture, hydration, glow, and reduction in fine lines. Often referred to as "Hydro-Lifting" or a "Glass Skin" effect.
Definisse Hydrobooster (Definisse Hydrobooster)
Role: Primarily for intense hydration and improving skin radiance, with a secondary benefit of mild collagen stimulation. Excellent for very dry or dehydrated skin.
Mechanism: Contains non-cross-linked HA and Glycerol. HA provides immediate and deep hydration, while Glycerol enhances the hydrating effect and promotes collagen stimulation to a lesser extent than Profhilo or Sculptra.
Result: Skin appears plump, dewy, and radiant, with fine lines caused by dehydration visibly reduced.
Medical-grade Skincare (Continuous Skincare): The Foundation for Sustained Youthfulness
No matter which procedure you choose, consistent daily skincare is the foundation for maintaining youthful skin and enhancing treatment results.
Role: Provides essential nutrients, antioxidants, and protective barriers to the skin. It helps repair daily damage, stimulates cell regeneration, and protects against environmental aggressors.
Key Ingredients:
Antioxidants (e.g., Vitamin C, Vitamin E, Ferulic Acid): Protect against free radical damage from UV and pollution.
Retinoids (e.g., Retinol, Tretinoin): Stimulate collagen production, accelerate cell turnover, and improve skin texture.
Peptides and Growth Factors: Signal skin cells to produce more collagen and elastin.
Hyaluronic Acid: Provides hydration and plumping effect.
Sunscreen: The most crucial step! Protects the skin from harmful UV radiation, which is the primary cause of premature aging and wrinkles.
Result: Regular use of appropriate medical-grade skincare helps maintain the results of treatments, slows down the aging process, and keeps the skin healthy and radiant in the long term.
Other Supporting Treatments (Combination Therapy for Maximum Results) At Entrio Clinic, we understand that sometimes the most effective results come from combining multiple treatment modalities. Depending on the patient's individual needs, we may recommend:
Laser and Energy-Based Devices (e.g., Fractional Laser, Pico Laser): Can improve skin texture, reduce pigmentation, and stimulate collagen on the surface.
Thread Lifts: For sagging skin, to provide an immediate lifting effect and stimulate collagen along the threads.
Platelet-Rich Plasma (PRP): Uses growth factors from your own blood to stimulate skin rejuvenation.
"In essence, managing wrinkles at Entrio Clinic is like being a skilled 'orchestra conductor.' We don't rely on just one instrument. Instead, we combine various 'instruments' (treatments) to play a harmonious symphony, ensuring that every note (skin layer) works together to deliver the most beautiful and youthful skin."
Morpheus8: Managing "Wrinkles" while "Lifting and Tightening Skin" and Improving "Skin Quality" Simultaneously!
orpheus8 is not limited to treating acne scars; it is also an excellent innovation for managing all types of wrinkles and lifting and tightening the skin concurrently. It truly provides comprehensive "Skin Remodeling."
Mechanism: As explained in the section on acne scars, the RF energy delivered deep into the dermal layer via tiny needles stimulates a significant amount of new collagen and elastin production. This results in overall firmer skin and a visible reduction in the appearance of various wrinkles.
Suitable for: Individuals with deep wrinkles, wrinkles caused by skin laxity, uneven skin texture, enlarged pores, and those who desire facial lifting along with wrinkle reduction.
Morpheus8 is like a 'machine' that can 'iron out' and 'rearrange' a wrinkled fabric, making it smooth and taut again, while simultaneously 'weaving new fibers' into the fabric, thereby strengthening the skin structure from within, leading to smoother and more youthful skin.
Dr. Nono's "Comprehensive Philosophy" at Entrio Clinic Ratchaprasong: Superior Treatment... for Truly "Beautiful Skin, Your Way!"
From my experience, "acne scars" and "wrinkles" often come with other complex skin issues, such as enlarged pores, uneven skin tone, laxity, or dehydration. Therefore, treating them with a single method often yields incomplete results.
At Entrio Clinic, Ratchaprasong Aesthetic Clinic, my team and I are committed to a philosophy of "Combination Therapy" that is meticulously designed and "personalized."
In-depth and Precise Problem Analysis: Every treatment begins with a detailed discussion and analysis of your skin condition. I will assess the type of acne scars, the depth of wrinkles, overall skin condition (e.g., pores, texture), volume loss, skin elasticity, facial expression habits, as well as your expectations and budget. I will use my knowledge of anatomy and experience to evaluate your facial structure holistically, so that the treatment not only addresses the problem but also enhances beauty in the most natural way possible.
Strategic Combination of Innovations:
Synergistic Effect: We will select procedures from various groups to work together effectively. For example, using Botulinum Toxin to manage expression lines while Morpheus8 remodels the overall skin, and Biostimulators gradually build collagen to address long-term volume loss. Or using Subcision to release deep acne scars before following with Morpheus8 to stimulate new tissue formation.
Sustainable and Natural Results: This combination allows us to manage skin problems in every dimension with maximum effectiveness. The results are not just about "solving problems" but about "elevating" overall skin quality visibly and naturally, because it stimulates your skin to "rejuvenate itself."
Attention to "Safety" and "Natural Results": I always prioritize patient safety. We choose only authentic products that meet international standards and the most advanced equipment. I am committed to delivering results that look "beautiful and natural," not making you look "changed" beyond recognition. Subtle improvements and preserving each individual's unique characteristics are at the heart of my work and the team at Entrio Clinic.
Why is Entrio Clinic, Ratchaprasong Aesthetic Clinic, the Best Choice for You?
Expert and Experienced Physicians: I, Dr. Chanapat Chinwachakitwanich, and the Entrio Clinic medical team possess deep knowledge and experience in the science of beauty, and we constantly update ourselves with new innovations and techniques.
Comprehensive Modern Innovations and Technology: We meticulously select only the best tools and products (such as Morpheus8, Sculptra, Profhilo, Juvelook, Botulinum Toxin, Dermal Fillers) to ensure we have a complete "arsenal" to manage all types of skin problems, be it "acne scars" or "wrinkles."
"Personalized" Care: We believe that the best treatment is one designed exclusively for you, not a one-size-fits-all solution.
Premium Atmosphere and Superior Service: At Entrio Clinic Ratchaprasong, you will receive a skincare experience in a luxurious, relaxing atmosphere and attentive service in every detail.
Downtown Location: Situated in the Ratchaprasong area, easily accessible and suitable for an urban lifestyle.
Your First Step Towards Smooth, Wrinkle-Free, and Youthful Skin Begins at Entrio Clinic Ratchaprasong!
Don't let "acne scars" and "wrinkles" undermine your confidence any longer. Having smooth, clear, and youthful skin is no longer a dream if treated correctly and precisely.
I invite everyone who is looking for an aesthetic clinic that is ready to care for you with a deep understanding of the science of beauty and bring you the most modern innovations... come consult with me at Entrio Clinic.
Together, we will meticulously analyze your skin problems, design the most suitable treatment plan, and collectively create "your beautiful skin" to glow once more. My team and I are ready to take care of you every step of this journey.
Entrio Clinic - Refined Aesthetic Experience "
We believe that true beauty comes from good skin health and an understanding of science."
📍 Location: https://maps.app.goo.gl/X9WpN51pnK5otKip8
4th Floor, Erawan Bangkok, Ratchaprasong Intersection (behind the Erawan Shrine), Bangkok.
💬 Line: @entrioclinic or click bit.ly/EntrioLine
📞 Tel: 097-154-2222
🌐 Website: entrioclinic.com
💻Facebook: facebook.com/EntrioClinic
📷 Instagram: instagram.com/entrioclinic/
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