The Synergy of Hyaluronic Acid & Polynucleotide (PN) Bio-Restructuring
As we age or are exposed to environmental pollutants, the dermal layer of the skin loses moisture and collagen, leading to dryness, enlarged pores, and fine lines. Surface-level care alone may not suffice. At ENTRIO CLINIC, we offer an innovative skin-restructuring treatment that combines the benefits of pure Hyaluronic Acid (HA) with Polynucleotides (PN)—a concentrated, pure DNA extract.
These bioactive substances work from within to repair the skin, stimulating fibroblasts to naturally produce collagen and elastin while retaining moisture beneath the surface. The result is hydrated, radiant "glass skin" that is resilient, strong, and sustainably healthy.
3 Keys to Skin Renewal
Deep Dermal Hydration
Restores natural hyaluronic reserves for long-lasting inner skin glow.
DNA Repair
Polynucleotides repair damaged skin and reduce inflammation beneath the skin's surface.
Fibroblast Activation
Strengthens fragile skin texture against daily environmental oxidants.
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PROGRAM
Hydro Booster
(Replenishes moisture from beneath the skin, locking in hydration for an instant bouncy, radiant look.)
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Focus: Concentrated Hyaluronic Acid designed to instantly bind water reserves within the dermis, smoothing fine dehydrated lines and restoring deep skin plumpness.
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Ideal For: Dehydrated skin types, dull texture, and patients seeking an immediate hydration surge.
PROGRAM
Plinest
(Helps repair and restore skin at a structural level)
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Focus: Premium Italian Polynucleotides engineered to stimulate fibroblast activity, repair ECM architecture, and enhance dermal thickness and elasticity.
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Ideal For: Skin laxity, compromised skin barrier and age-related structural depletion.
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PROGRAM
Vitaran
(Skin-revitalizing injection for a dewy glow, using salmon DNA extract)
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Focus: Ultra-pure PN formulation tailored to improve skin texture grain, shrink pore diameter, and promote a luminous "Glass Skin" complexion.
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Ideal For: Uneven skin surface, fine micro-wrinkles, and overall complexion refinement.
100% Doctor-Led Diagnostic Analysis
Dr. Chanaphat Chinvetkitvanit, M.D. (License No. 60686) personally conducts thorough skin analysis to tailor precise injection dosages 1-2 CC and micro-point vectors according to your specific dermal needs.
Verified Authentic Bio-Injectables
Absolute transparency. Every vial and box of Program Hydro Booster, Program Nucleofill, or Program Vitaran is unboxed and verified via official scannable QR codes right in front of you.
Gentle Micro-Injection Protocol
Administered with specialized ultra-fine needles and topical anesthesia under Dr. Chanaphat Chinvetkitvanit, M.D. (License No. 60686)'s meticulous technique, ensuring high comfort and minimal downtime.
Who is the HA & Polynucleotide suitable for?
The Hydro Booster program is for those with dry, dehydrated skin, makeup that doesn't stay on, and who need intensely hydrated, plump skin.
The Plinest Program is for individuals with skin atrophy, thin skin, lack of elasticity, fine wrinkles, and who desire deep skin repair with highly pure Polynucleotide (PN) from Italy.
The Vitaran Program is for those who want to rejuvenate their skin in the Korean style, refining skin texture, reducing pores, and creating Glass Skin.
Those who wish to strengthen their skin barrier in conjunction with a skin tightening device should undergo a skin assessment by a doctor.
At a Glance
Anesthesia
Medical grade topical anesthetic
( 30 - 45 minutes )
In conjunction with cold compresses.
Duration of treatment
( Treatment Time )
20 - 30 minutes
Recovery period
(Downtime)
Small bumps at the injection site will disappear within 24 - 48 hours. You can apply makeup as usual.
Duration of result retention
3 - 6 months
( Recommended to do this 3 times consecutively )
FAQ
HA & Polynucleotides
Q1
How do HA and Polynucleotides (PN) differ, and can they be combined?
Hyaluronic Acid focuses on immediate dermal hydration and volume retention, while Polynucleotides actively repair stimulate collagen synthesis. They can be synergistically combined or paired with energy-based devices like Program XERF or Ultherapy Prime for comprehensive rejuvenation under Dr. Chanaphat Chinvetkitvanit, M.D. (License No. 60686)'s supervision.
Q2
What is the post-treatment recovery and downtime?
Mild micro-papules at injection sites typically absorb naturally within 24-48 hours. Normal daily activities can be resumed immediately.
Q3
When will I start seeing results, and how often should I do it?
You can feel your skin becoming more hydrated and plump within 3-7 days after treatment, and full skin repair results will be visible in 2-4 weeks. We recommend a total of 3 treatments, spaced 3-4 weeks apart, to allow for collagen accumulation and longer-lasting results.