Dr. Nono: From the Classroom to the Clinic – Unlocking the Secrets of Thai Skin Beauty as a Dermatologist
- SPARK IDEA Digital Marketing

- Dec 17, 2025
- 10 min read

Hello! I am Dr. Chanaphat Chinvechkitvanich, or as many of my patients familiarly know me, Dr. Nono. Today, I would like to take on the role of both a doctor and a friend, ready to share the story of my journey with you.
Looking back to my medical school days at the Faculty of Medicine Ramathibodi Hospital, Mahidol University, I learned every branch of medical science. However, the one thing that sparked a special interest in me was "Dermatology." I discovered that the skin is not merely an organ covering the body, but a mirror reflecting a person's health, lifestyle, and inner feelings.
With this deep interest, I decided to further my studies with a Master of Science in Clinical Dermatology at Cardiff University in the United Kingdom. Learning from world-class experts and conducting intensive research gave me a profound understanding that true beauty must come from the foundation of strong, healthy skin. That was the starting point that led me back to Thailand with a determination to use this knowledge for maximum benefit, resulting in the founding of Entrio Clinic, an aesthetic clinic in the Ratchaprasong district.
In this article, I will take you deep into the key issues I often encounter in the examination room—from common problems like uneven skin texture and large pores to how to correctly choose a Dermatologist and an Aesthetic Clinic. My goal is to help you discover the path to beautiful skin with confidence and safety.
Part 1: Opening Up... Why are Uneven Skin Texture and Large Pores Huge Problems?
From my years of experience as a Dermatologist at this Ratchaprasong aesthetic clinic, I have found that the issues causing many patients to lose confidence daily aren't just wrinkles, but clearly visible problems like uneven skin texture and large pores.
Many people might think these are normal age-related issues that must be accepted. In reality, the root causes are more complex than you might think. Understanding the true causes will help us choose the most precise and effective treatments.
1.1 Unlocking the Root Cause of ‘Large Pores’
Large pores are not caused solely by oily skin; they result from multiple factors directly affecting the skin structure.
Excess Sebum Production: The Sebaceous Glands produce oil to maintain skin moisture. However, when too much oil is produced, it mixes with dirt and dead skin cells, causing clogs that permanently stretch and widen the pores.
Loss of Collagen and Elastin: Collagen and Elastin are crucial proteins that act as the structure supporting skin firmness and elasticity. As we age, the body produces less of these proteins, causing the skin around the pores to lose firmness and collapse, making the pores appear larger and deeper.
Use of Unsuitable Products: Using products that are harsh or dry out the skin too much stimulates the skin to produce more oil to compensate for lost moisture, leading to wider pores.
External Factors: UV rays in sunlight are major culprits that destroy Collagen and Elastin, accelerating skin deterioration. Additionally, squeezing acne or touching the face frequently damages the skin and pores, causing them to expand.
1.2 Causes of ‘Uneven Skin Texture’
For uneven skin texture, the problem usually stems from damage within the dermis layer, which is more difficult to solve than dry or dehydrated skin.
Acne Scars: This is the primary cause of uneven skin. When acne inflammation is severe, the body undergoes an incomplete repair process, creating fibrosis (scar tissue) under the skin that pulls the surface down, forming depressions or pitted acne scars. This requires technology capable of penetrating deep to correct the skin structure.
Accumulation of Dead Skin Cells: When dead cells are not properly exfoliated, they clog pores, making the skin look dull and rough. This also leads to further comedonal acne.
Dehydration: Dehydrated skin lacks elasticity and plumpness, making surface irregularities and texture issues more apparent.
Skin Type and Genetics: Genetic factors and individual skin types also play a role in determining pore size and susceptibility to uneven skin texture.
Treating these problems isn't just about applying cream; it requires precise diagnosis and the use of appropriate technology to restore the skin from its true root cause.
Part 2: Superior Solutions – Targeted Skin Management at Entrio Clinic, Ratchaprasong
In the previous section, we delved into the causes of uneven skin and large pores. In this part, I will introduce methods to solve these problems using modern, internationally standardized technologies available at Entrio Clinic, a leading aesthetic clinic in Ratchaprasong.
As a Dermatologist, I believe effective treatment starts with a correct diagnosis and selecting tools tailored to each patient's specific problems.
2.1 Fractional Laser Group (Fractora): Creating Smooth New Skin

After understanding that uneven skin and acne scars are caused by deep skin damage, I want to introduce a highly effective, targeted treatment technology called Fractora.
What is Fractora? Fractora is an advanced skin rejuvenation technology with a high safety profile. It combines Radio Frequency (RF) and Microneedling. The principle involves releasing RF energy through tiny needles directly into the dermis layer, allowing for targeted skin correction without damaging the upper skin layer.
Mechanism of Action: Fractora restores smoothness to the face through two key mechanisms:
Breaking Down Subcutaneous Fibrosis: For severe acne scars, fibrous tissue pulls the skin down. The RF energy delivered via needle tips breaks down this fibrosis, releasing the skin tension and allowing it to fill in more easily.
Stimulating New Collagen: The heat energy from RF rapidly stimulates the creation of new Collagen and Elastin in the skin layers. This restores damaged skin structures, making them stronger and more elastic, resulting in plump skin and naturally shallower acne scars.
Who is Fractora suitable for?
Those with acne scars or scarring (both shallow and deep).
Those with large pores.
Those with fine wrinkles on the face.
Those wanting to improve skin texture for a smoother appearance.
Dr. Nono’s Advice: Treatment with Fractora should be performed by an expert doctor to assess the appropriate depth for energy delivery for safety and optimal results. At Entrio Clinic, we are ready to provide detailed consultations before you decide.
2.2 IPL Laser Group (Lumecca): Eliminating Pigment and Brightening Skin

If you have uneven skin tone due to dark spots, redness, or sun dullness, I recommend Lumecca, one of the most powerful IPL (Intense Pulsed Light) technologies currently available.
What is Lumecca? Lumecca is an advanced IPL technology capable of resolving pigment issues precisely and up to 3 times faster than standard IPL machines. With high energy and a wavelength optimized for pigment absorption, it effectively treats melasma, freckles, and dark spots.
Mechanism of Action: Lumecca helps the skin look bright and smooth through specific principles:
Targeting Abnormal Pigment: Light energy is transmitted through the skin to target abnormal pigments like Melanin (in melasma/freckles) and Hemoglobin (in redness/capillaries).
Pigment Breakdown: When the energy is absorbed, heat is generated, shattering the pigment into tiny particles which the body then naturally eliminates.
Collagen Stimulation: Beyond pigment, the heat stimulates new Collagen production, making the overall skin look firmer and healthier.
Who is Lumecca suitable for?
Those with melasma, freckles, and dark spots from sunlight.
Those with redness from acne or capillaries causing uneven skin tone.
Those wanting a bright, even complexion.
Dr. Nono’s Advice: Lumecca is a quick procedure with minimal pain. However, for the safest and best results, it should be performed by an expert Dermatologist to assess skin condition and plan the appropriate treatment.
2.3 Lifting & Tightening Group (Ulthera Prime, Morpheus8, Oligio & XERF): Tightening Pores and Building Collagen

As a Dermatologist, I have found that a primary cause of large pores is skin losing elasticity and age-related Collagen loss. These issues can be directly addressed with cutting-edge lifting technologies. At Entrio Clinic, we utilize 4 key technologies: Ulthera Prime, Morpheus8, Oligio, and XERF.
Ulthera Prime: Deep Lifting... For Sustainable Youth

I am proud to present Ulthera Prime, a technology that lifts and tightens skin from the deep layers precisely and effectively without surgery.
What is Ulthera Prime? It uses Micro-Focused Ultrasound with Visualization (MFU-V). It is precise and penetrates deep layers that other technologies cannot reach, recognized internationally as the Gold Standard for non-surgical lifting.
Mechanism of Action:
Reaching the SMAS Layer: Sound waves are sent precisely to the SMAS (Superficial Musculo-Aponeurotic System) layer—the same layer surgeons lift during a facelift. This causes tissue contraction, starting the lifting process.
New Collagen Stimulation: Heat triggers the body to continuously produce new Collagen and Elastin for 3-6 months, making the skin truly elastic and strong.
Real-time Visualization: Doctors can see the skin layers in real-time on a screen, ensuring energy is delivered to the correct depth and location.
Who is Ulthera Prime suitable for?
Those with sagging skin, drooping cheeks, and deep nasolabial folds.
Those wanting to lift the face and neck without surgery.
Those wanting a sharper, more defined jawline.
Morpheus8: Tightening Pores and Smoothing Skin

For large pores, uneven skin from scars, or lack of elasticity, Morpheus8 is highly regarded in the dermatology world.
What is Morpheus8? It is a Deep RF Microneedling technology capable of adjusting the depth of energy delivery to suit individual skin problems.
Mechanism of Action:
Creating Micro-lesions: Tiny gold-coated needles create micro-channels, triggering natural repair.
Sending RF Energy Deep: Radio Frequency heat is released from the needle tips into the dermis. This rapidly stimulates Collagen and Elastin, breaks down scar fibrosis, and tightens the collagen structure around pores, making them permanently smaller.
Who is Morpheus8 suitable for?
Those with acne scars (shallow and deep).
Those with large pores seeking permanent reduction.
Those with fine wrinkles and lax skin.
Oligio: Restoring Firmness and Youthfulness

If you have sagging skin or large pores but want a treatment with minimal pain and no downtime, I recommend Oligio.
What is Oligio? A Monopolar RF technology developed to firm skin, reduce wrinkles, and rejuvenate the complexion naturally.
Mechanism of Action:
Volumetric Heating: Oligio sends RF energy to create consistent heat in the Dermis. This causes immediate contraction and realignment of existing Collagen fibers, giving a firmer feel instantly.
Long-term Collagen Stimulation: Heat accumulation stimulates continuous new collagen production, leading to long-term firmness.
Who is Oligio suitable for?
Those with mild to moderate sagging.
Those wanting to reduce fine wrinkles.
Those wanting smaller pores.
Those with no time for downtime and who prefer less pain.
XERF: Structural Skin Tightening... Painless, No Numbing Cream Needed

For patients wanting perfect skin but fearing pain, XERF is the answer. This is the New Generation of lifting, currently trending in dermatology.
What is XERF? XERF is a Structural Skin Tightening technology using Monopolar RF with a unique Dual-Frequency (6.78 MHz and 2 MHz). It treats all skin layers, from superficial to deep fat layers, without needles or surgery.
Mechanism of Action:
Dual-Frequency Lifting: Combining two frequencies allows XERF to distribute heat energy thoroughly into the dermis and fat layers deeper than standard RF. This stimulates structural tightening from within.
Painless & Never-Numb™ Experience: With the Wave Fit Pulse system adjusting to skin resistance and ICD Cooling, XERF is "painless" and requires "no anesthesia." You feel only a comfortable warmth, and there is no downtime—you can apply makeup and go out immediately.
Who is XERF suitable for?
Those with sagging skin, nasolabial folds, or undefined jawlines.
Those who are "afraid of pain" or "afraid of needles" and dislike numbing cream.
Those wanting to reduce cheek fat/double chin while tightening.
Dr. Nono’s Advice: Choosing the right technology for large pores and sagging requires consulting an expert Dermatologist. At Entrio Clinic, we evaluate your facial structure to design the best treatment plan for you.
Part 3: More Than Just Procedures – Why Choosing the Right Dermatologist and Aesthetic Clinic Matters

From my experience as a Dermatologist, the most important factor isn't just the machine, but the doctor's understanding of diagnosis and planning.
1. Knowledge and Expertise
Injecting substances or using lasers isn't something just anyone can do effectively. An expert Dermatologist diagnoses problems accurately—not just looking at the surface, but understanding the mechanism of the issue. I believe my knowledge and experience from my Doctor of Medicine degree and Master’s in Clinical Dermatology from the UK allow me to care for patients effectively.
2. Safety Comes First
A good Aesthetic Clinic must prioritize safety. At Entrio Clinic:
Authentic Products: We use only FDA-approved products (Thai and International).
Standardized Equipment: Every device is inspected and maintained to international standards.
Hygiene: We strictly maintain the cleanliness of the venue and equipment to prevent infection.
3. Personalized Treatment Plans
Every face is unique. A good Dermatologist won't use a "One Size Fits All" program. We evaluate skin condition, facial structure, lifestyle, and individual needs to design a plan that yields the most natural results.
Part 4: Conclusion from ‘Dr. Nono’: Sustainable Skin Beauty Starts at Entrio Clinic

We have discussed everything from understanding uneven skin and large pores to selecting the right technology and the right Dermatologist. I hope this information helps you understand true skin care.
I always believe that skincare isn't just about external beauty; it is an investment in long-term confidence and health. Deciding to start caring for yourself with modern Aesthetic Technology is important, and choosing a trustworthy Aesthetic Clinic is equally vital.
I, Dr. Nono, and the team at Entrio Clinic, the aesthetic clinic in Ratchaprasong, are committed to providing the best for every patient. We are ready to be part of your journey to beautiful skin with the dermatological expertise I have accumulated and internationally standardized technology.
If you are looking for an Aesthetic Clinic that prioritizes safety, expertise, and sustainable results, I invite you to consult with us at Entrio Clinic. We would be delighted to take care of you and help restore your beautiful, healthy skin and confidence in every aspect of life.
Entrio Clinic - Refined Aesthetic Experience
“We believe that true beauty comes from healthy skin and an understanding of science.”
📍 Location: https://maps.app.goo.gl/X9WpN51pnK5otKip8
4th Floor, Erawan Bangkok, Ratchaprasong Intersection (Behind Erawan Shrine), Bangkok.
💬 Line: @entrioclinic or click bit.ly/EntrioLine
📞 Tel: 097-154-2
🌐 Website: entrioclinic.com
💻 Facebook: facebook.com/EntrioClinic
📷 Instagram: entrioclinic or click instagram.com/entrioclinic/








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